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Fjqm Defects in Cell s  Waste Disposal System  Linked to Parkinson s
WASHINGTON DC:The US Navy is quietly pushing ahead with a radical new cannon that one day could transform how wars are fought, even though some Pentagon officials have voiced concerns over its cost and viability.Named the railgun, the weapon in question represents a paradigm shift in ballistic technology. Instead of using gunpowder and explosive charges to shoot a shell from its barrel, it employs vast amounts of electromagnetic energy to zoom a projectile along a set of copper-alloy rails.Thanks to four small fins on its r adidas campus noir ear, the hefty round  nb mujer can then be guided toward a moving object -- such as an enemy ship, drone or incoming ballistic ugg boots damen  missile -- relying purely on the kinetic energy from its vast momentum to destroy the target.France to build Australia subs but US to arm themUltimately, scientists expect the railgun rounds to travel at speeds up to Mach 7.5, which at 5,700 mph (9,100 kph) is more than seven times the speed of sound, and cover a distance of about 100 miles (160 kilome Applying mathematical models used for studying the galaxies or interactio yeezy 350 ns between elementary particles, rese dunk nike high archers at the Institute of Neuroscience of the Universitat Autònoma de Barcelona (UAB), in collaboration with Massachusetts General Hospital, Boston, have analyzed the spatial distribution of astrocytes: brain cells that are essential for the correct functioning of neurons. This research is published in Proceedings of the National Academy of Sciences.The scientis converse all star ts observed that these cells seem to be repelled by the amyloid plaques. These plaques are associated with development of Alzheimer's disease and several therapeutic strategies are aimed at reducing their formation and eliminating them. Up to now researchers thought that the astrocytes migrated towards the amyloid plaques and devoured them, so that reinforcing their activity could be a good remedy against development of the disease. However, this analysis of astrocyte distribution shows the opposite: the ast

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Btdo Alnylam Announces USPTO Issues Patent Covering RNAi Therapeutics
PESHAWAR:Fading audience interest towards Pashto films has forced producers to stop churning out movies that may prove disastrous at the box office in Khyber-Pakhtunkhwa.Bad quality films seem to be the last nail in the coffin in whatever remains of the Pashto film circuit in the provi adidas campus gr眉n nce. The PAF Cine adidas samba vegan ma has been closed for the past one year, while four cinemas in Nowshera and one in Mardan have been shut down indefinitely. There were also two theatre houses in Swat that聽are no longer functional.鈥淭he cost of doing business is extremely high now,鈥?Rehan Khan, contractor of Capital Cinema told聽The Express Tribune. 鈥淐apital Cinema had been screening two shows a day of a Pashto movie, c adidas campus bianche harging Rs100 per ticket. But there were not more than 10 people in the cinema hall, and we are struggling to meet the expenses. We are now trying to figure out how to pay monthly bills and salaries.鈥滳inema owners fear losses as Raees leaks on cable, FacebookSituated in a historical building in Saddar, the c The Wyss Institute for Biologically Inspired Engineering at Harvard University has announced a cross-institutional consortium to map the brain's neural circuits with unprecedented fidelity. The consortium is made possible by a $21 million contract from the Intelligence Advanced Research Projects Activity (IARPA) and aims to discover the brain's learning rules and synaptic 'circuit design', further helping to advance neurally-derived machine learning algorithms.The consortium will leverage the Wyss Institute's FISSEQ (fluorescent in-situ sequencing) method to push forward neuronal connectomics, the science of identifying the neuronal cells that work together to bring about specific brain functions. FISSEQ was developed in 2014 by the Wyss Core F yeezy aculty member George Church and colleagues and, unlike traditional sequenc asic schuh ing technologies, it provides a method to pinpoint the precise locations of specific RNA molecules in intact tissue. The conso nike dunk low rtium will harness this FISSEQ capability to a

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Toml Police-public interaction: Recognising those who help keep roads safe
KARACHIakistan鈥檚 oil production reached a two-year high of 97,000 barrels per day in December 2016 after oil and gas exploration and production companies geared up their drive to find new deposits of hydrocarbons in the country.Nabeel Khursheed, an analyst at Topline Securities, said in a note to his clients that the surge in production became  stanley-cup possible with find of new oil reserves from Nashpa and Mardan Khel fields.鈥淏oth fields added around 11% to December 2016鈥檚 oil production, a cumulative flow of around 10,000 barrels per day (bpd) of oil,鈥?he said.The production meets around 20% of domestic demand. The remainder is met through imported crude oil and finished petroleum products.Rebounding oil prices spell bad newsLocal production was reportedly hovering below 90,000 bpd in November. This was standing at 87,000 bpd in the previous fiscal year en adidas sambarose ded June 30, 2016 and 95,0 adidas campus 00 bpd in the year before. The decline in production in fiscal year 2015-16 (FY16) was seen after oil producing  Scale-up Systems Ltd. announced it has entered into a multi-year agreement with ScienView Co. Ltd. to provide DynoChem庐 software, training and process development suppor adidas yeezy t services to the Chinese pharmaceutical industry.The motivation behind the agreement is to provide a dedicated local presence to help Chinese users to obtain maximum value from DynoChem鈥檚 tools. The initial team in the Beijing and Shanghai offices will be led by Dr. Jinjun Wang for Training & Technical Support and Jack Ma on the Business side.According to Scale-up Systems CEO Dr. Joe Hannon, 鈥淲e have been looking for a partner in China that, like our company, specialises in working with and understands the needs of the pharma and life sciences industry. We are therefore delighted to be w ciabatte yeezy orking with ScienView.鈥漇cale-up Systems COO Dr. Steve Hearn said 鈥淲hat made ScienView stand out to us was the value it placed on hiring high quality training and support staff across multiple domains.鈥漇cienView鈥檚 Vice President  nike dunk high of I

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Vgwr Indian ;orphans; face abuse, neglect in Tamil Nadu care homes, activists say
BATON ROUGE, LA/MINNEAPOLISrotests against the shootings of two black men by police officers shut down main arteries in a number of US cities on Saturday, leading to numerous arrests, scuffles and injuries in confrontations between police and demonstrators.Undeterred by heightened concerns about safety at protests after a lone gunman killed five police officers in Dallas Thursday night, organizers went ahead with marches in the biggest metropolis, New York City, and Washington DC, the nation's capital, among other cities. adidas campus beige Police officer who shot black man was reacting to gun, not race: lawyerIt was the third straight day of widespread protests after the fatal shooting of Alton Sterling, 37, by police in Baton Rouge on Tuesday and the death of Philando Castile, 32, on Wednesday night in a St. Paul, Minnesota suburb, cities which both saw heated protests on Satur ugg fellboots day.The most recent shooting deaths by police co adidas campus 00s me after several years of contentious killings by law enforcement officers, in Stanford University researchers have discovered a rapid and sustainable way to synthetically produce a promising cancer-fighting compound right in the lab. The compound鈥檚 availability has been limited because its only currently known natural source is a single plant converse  species that grows solely in a small rainforest region of Northeastern Australia.The compound, designated EBC-46 and technically called tigilanol  newbalance 530 tiglate, works by promoting a localized immune response against tumors. The response breaks apart the tumor鈥檚 blood vessels and ultimately kills its cancerous cells. EBC-46 recently entered into human clinical trials following its extremely high success rate in treating a kind of cancer in dogs.Given its complex structure, however, EBC-46 had appeared synthetically inaccessible, meaning no plausible path seemed to exist for producing it practically in a laboratory. However, thanks to a clever process, the Stanford researchers demonstrated for the first time air forces  how to chemically trans

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Buup NIH Study Finds Avastin and Lucentis are Equally Effective in Treating AMD
In response to Saturday鈥檚 terrorist attack on security forces in which 15 people including eight soldiers were martyred and 25 others injured, Balochistan Chief Minister Nawab Sanaullah Zehri adidas samba homme  has vowed to chase all terrorists and their facilitators out of their hideouts and bring them to justice.鈥淭errorism is a global problem now and not confine nb d to Pakistan alone,鈥?Zehri said while addressing a news conference at the CM Secretariat on Sunday. He was flanked by Interior Minister Ahsan Iqbal, provincial ministers, and others.The chief minister said that he was at the rally of ousted prime minister Nawaz Sharif in Lahore when terrorists targeted the truck of security forces. 鈥淲e hurried back to Quetta on the instructions of [Sharif].鈥?5 martyred, 25 injured in bomb attack on army truck in QuettaZehri, accompanied by the interior minister, had returned to Quetta late on Saturday night.The Balochistan CM said, 鈥淭he security situation has imp adidas samba blanche roved immensely as compared to that from 2011 to  Scientists have uncovered a novel antibiotic-free approach that could help prevent and treat one of the most widespread bacterial pathogens, using nanocapsules made of natural ingredients.Helicobacter pylori (H. pylori) is a bacterial pathogen carried by 4.4 billion people worldwide, with the highest prevalence in Africa, Latin America and the Caribbean. Although the majority of infections show no symptoms, if left untreated the pathogen can cause chronic inflammation of the stomach lining, ulcers and is associated with an increased risk of gastric cancer.Bacteria p yeezy 350 osting threats to human health In 2017, the World Health Organisation included H yeezy 350 . pylo yeezy boost 350 ri on its list of antibiotic-resistant "priority pathogens" 鈥?a catalogue of bacteria that pose the greatest threat to human health and that urgently need new treatments.Current treatments involve multi-target therapy with a combination of antibiotics, but this has promoted the emergence of resistant strains.Now, UK and German scientists ha

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Sxbb Herpes-loaded Stem Cells Used to Kill Brain Tumors
PESHAWAR:Keeping in view the influx of files and data, modern technology will be put to use to introduce a 鈥榩aperless system鈥?at the health secretariat.鈥淚t will reduce the burden and will make tracking of files easy,鈥?a senior health official told The Express Tribune, requesting anonymity since he was not authorised to talk to the media. He added several complaints were filed by different people t adidas campus rouge hat their files could not be traced. More often than not, files would go missing.鈥淎 number of files went missing,鈥?he said. 鈥淸Such a situation] would create problems for the officials.鈥漈he official maintained that by switching to a 鈥榩aperless system鈥? the risk of losing files will be reduced and all documents will be available on a single click.E-Office InitiativeHealth officials told T adidas campus 80s he Express Tribune the system 鈥?called E-Office Initiative 鈥?has initially been inaugurated at the health secretariat so that all the data is saved in computers.The new system will be  adidas campus 80s gradually expanded to the K AB SCIEX, with its partners Phenomenex and Peak Scientific, announced that they will be bringing the European MASStastic Voyage Tour to Ireland. The event will bring together leading separation scientists, instrumentation experts and applic nike dunk high ation specialists from academia and industry in sectors such as biopharma, food and clinical medicine to discuss new opportunities for advancing research and for fostering new collaborations. The ISSC鈥檚 event, at Dublin City University (DCU) on November 12, will be attended by up to 100 delegates from multi-national corpora dunks nike store tions, local government agencies and industry trade organizations.The MASStastic Voyage Tour 鈥?a sophisticated lab-on-wheels 鈥?will be making a series of scheduled stops at Cork and Dublin in earl adidas yeezys y November, providing 鈥渙pen house鈥?opportunities for anyone interested in using mass spectrometry and separation science to solve analytical challenges. On board the MASStastic Voyage mobile lab are the latest innovations in analytical ins

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Pakistan Army officials on Sunday recovered a huge cache of  new balance hombre arms and ammunition in聽North Waziristan Agency."Army troops recovered another huge cache of arms and ammunition which had been left behind by terrorists," Inter Services Public Relation (ISPR) said."The ammunition was recovered during sanitisation of village Shirrani village in Dattakhel, North Waziristan Agency," the statement added.Army asks citizens to assist Rangers in eliminating terror from PunjabOn Febru adidas samba mujer ary 22, the military announce ugg ultra mini d the launch of Operation Radd-ul-Fasaad in response to a spike in terrorist attacks across the country over the past month. The operation aims to indiscriminately eliminate all threats from the country and consolidate gains made during previous military operations.While Operation Radd-ul-Fasaad is being carried out across the country, the fact that the decision to launch it was taken during a meeting at the corps headquarters in Lahore suggests that Punjab is central to the new offensive. Ma This occurs at  nike dunk low a precise stage 鈥?cytokinesis 鈥?when the cell splits into two new daughter cells. It was observed by a team of researchers including Gilles Hickson, an assistant professor at the University of Montreal's Department of Pathology and Cell Biology and researcher at the CHU Sainte-Justine Research Centre, his assistant Silvana Jananji, in collaboration with Nelio Rodrigues, a PhD student, yeezy foam  and Sergey Lekomtsev, a postdoc, working in the group led by Buzz Baum of the MRC Laboratory for Molecular Cell Biology at University College London.Cell division is fundamental to all life forms: the human body develops from a single cell that divides billions of times to generate all tissue types, and some of these cells continue to divide billions of times every day throughout life. For the moment, however, the molecular mechanisms involved are incompletely understood, and it was unknown until now that chrom dunk chaussure osomes could play an active role at this step in cytokinesis.Flawless divisionIn

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Rhym A new experimental system sheds light on how memory loss may occur
LAHORE:There鈥檚 another date for Greater Iqbal Park inauguration. And this time it鈥檚 December 2. After announcement of several opening dates, the renovated park is likely to finally open its gates to the public. If everything goes according to plan that is.On Thursday, Lahore鈥檚 Parks and Horticulture Authority (PHA) proposed yet ano ugg boots ther date for the formal in adidas samba uomo auguration of the massive project in consultation with the Lahore division commissioner.PHA Director-General Shakeel Ahmed told The Express Tribune that the new date had been conveyed to the Chief Minister Office, which would confirm the availability of the prime minister for the inauguration.He said the park was ready to open its door as most development works had been completed. The authority, in collaboration with th new balance bleu e city administration, would make arrangements for the launch once it gets the green light from Islamabad.The authority had proposed November 9 and November 12 as inauguration dates but had to postpone the ceremony ow Africa鈥檚 rice sector has major opportunities to increase its yield gains through improved agronomic practices while avoiding massive land conversion, a study by international scientists including a H yeezy usker co-investigator finds. The production advances can be important in meeting A adidas yeezys frica鈥檚 projected food needs and reducing dependence on imports, the researchersconcluded.Rice demand in Africa is projected to more than double over the next 25 years due to population growth and increased rice consumption. At present, Africa imports nearly 40% of itsrice.鈥淣early 15 million hectares of rice are waiting for yield improvement in Afr adidas yeezy ica, but no yield gain can be achieved without better agronomy,鈥?said Patricio Grassini, the University of Nebraska鈥揕incoln professor of agronomy who coordinated the team working on the research study,鈥淚ntensifying rice production to reduce imports and land conversion in Africa,鈥漰ublished in NatureCommunications.Want more breaking news?Subscribe to Technology Network

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Zoda Polyplus-transfection Obtains an AFM Grant for the Development of its Gene/Drug Delivery Tool
SAN FRANCISCO:Oculus on Tuesday announced it is ramping up availability of its Rift virtual reality gear and planning a major conference in October for developers making software for it.Facebook-owned Oculus said that all pre-ordered Rift headsets have been sent to buyers, and promised that new orders made online at oculus.com will ship within four business days."We want to apologise for the delays in getting Rifts to doorsteps," the Oculus team said in a blog post.Announcing Oculus Connect 3 and Rift Availability Update! https://t.co/VZhjkIOHzD pic.twitter.com/sfwogw5c0N— Meta Quest (@MetaQuestVR) July 12, 2016Oculus began selling its Rift virtual reality headsets earlier this year for $599, a price which does not include the cost  nb of a computer that can handle the processing and graphics demands of the technolog ugg fellboots y.Facebook adds 360- new balance 480 degree photos to newsfeedOculus is also increasing inventory at US shops, saying that people should be able to get their hands on Rift at select Micro Hemispherx Biopharma has announced that it h yeezy foam as reached an agreement with Avrio Biopharmaceuticals to serve as an additional contract manufac af1 shoes turer of Hemispherx's experimental drug, Ampligen庐, also known by its generic name rintatolimod. Avrio, an FDA inspected facility, has the capabilities for the compounding and fill/finish of sterile clinical and commercial grade Ampligen庐 to satisfy the Company's ongoing domestic clinical studies as well as the recently initiated Early Access Program (EAP) in Europe and Turkey.This agreement with Avrio should allow Hemispherx to rapidly replenis nike dunk h its Ampligen庐/rintatolimod inventory. Serving the EAP, outside of the United States, is especially important because it has the potential to generate positive cash flow on EAP transactions while Hemispherx seeks commercial approval for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) in the United States, Argentina, and elsewhere.Thomas Equels, Hemispherx CEO, commented, "We are pleased to be wo

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A large black hole has been discovered in the middle of our galaxy. If confirmed, it would be the second biggest spotted in our neighbourhood.The find could lea new balance mujer d to the resolution of major mysteries regarding black holes by gi newbalance 530 ving scientists a chance to examine how they form. A large, toxic gas cloud was found swirling in the middle of the galaxy. Its strange movement signaled towards a huge 鈥榗ompact object鈥?at the centre, which scientists suspect of being a black hole.Astronomers piece together first image of black holeAstronomers believe that large galaxies like the Milky Way may contain black holes which could be a billion tim stanley-cup es larger than the sun, but they have not yet been able to figure how the phenomenon occurs. By having an opportunity to examine one in our own solar system, scientists may be able to discover how.A black hole for assistance?Large black holes 鈥?known as intermediate-mass black holes, or IMBHs 鈥?are believed to form after smaller black holes merge together to fo AmaxaandPromega have announced an agreement to develop applications that will provide cell biologists broader access to monitor cell signaling events in difficult-to-transfect cells, including stem cells, cancer cells and primary cells. Integrating their technologies in luminescence-based assays and transfection methodologies will simplify transfection of reporter genes and assay development in these difficult-to-transfect cell types.Amaxa鈥檚 Nucleofector庐 Technology enables unprecedented transfection capability and consistent performance in applications involving dunk nike store  more biologically relevant mammalian syst yeezy 500 ems, such as primary cells and stem cells.鈥淲ith the Nucleofector庐 Technology, transfection efficiencies of up to 95% using DNA and 99% using siRNA oligonucleotides can be achieved in difficult-to-transfect cells. Thus, the combination of Promega and Amaxa technologies will enable researchers to obtain much more signi dunk nike store ficant results with physiologically relevant cells rather than more art