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Ajax Kabul peace process: Taliban safe havens inside not outside Afghanistan, says Maleeha
  For proteins, appearance matters. These im yeezy schuh portant molecules largely form a cell鈥檚 structures and carry out its functions: proteins control growth and influence mobility, se yeezy 350 rve as catalysts, and transport or store other molecules. Comprised of long amino acid chains, the one-dimensional amino acid sequence may seem meaningless on paper. Yet when viewed in three dimensions, researchers can see what a protein鈥檚 structure is and how a protei yeezy slide n鈥檚 structure, and particularly the way it folds, determines its functions.There are close to 15,000 protein families 鈥?groups of families that share an evolutionary origin 鈥?in the database Pfam. For nearly a third (4,752) of these protein families, there is at least one protein in each family that already has an experimentally determined structure. For another third (4,886) of the protein families, comparative models could be built with some degree of confidence. For the final third (5,211) of the protein families in the database, however, no structur  RAWALPINDIolitical leadership of the garrison city is all set to celebrate Eidul Azha with religious fervour and zeal. In pursuance of the precedent set by Hazrat Ibr adidas samba blanche ahim, political leaders have bought sacrificial animals to their own liking. Awami Muslim League (AML) chief Sheik campus adidas h Rasheed has purchased two camels to sacrifice on Eid. He will be offering Eid prayers at Liaquat Bagh. Pakistan Muslim League-Nawaz (PML-N) leader Hanif Abbasi will be offering his Eid prayers at Jamia Mosque of Satellite Town and latter slaughter two goats as sacrifice to fulfil the religious obligation. Another prominent leader of PML-N in the city, Sheikh Arsalan will offer Eid prayers in Jamia Masjid of his locality and later sacrifice two bulls and two goats in the name of Allah Almighty. Pakistan Peoples Party City P new balance bleu resident Babar Jadoon will offer sacrifice of a bull and three goats after saying Eid prayers at main mosque of Hazara Colony. Pakistan Tehreek-e-Insaf (PTI) district president Zahid Husse

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Obzu After 20 years, Peshawar prepares to bid farewell to Kabuli burger
  Toronto scientists h yeezys slide ave mapped the genes allowing cancer cells to avoid getting killed by the immune system in a finding that paves the way for the development of immunotherapies that would be effective for larger patient populations and across different tumour types."Over the last decade, different forms of immunotherapy have emerged as really potent cancer treatments but the reality is that they only generate durable responses in a fraction of patients and not for all tumour types," says Jason Moffat, a professor of molecular genetics in the Donnelly Centre for Cellu nike store dunk lar and Biomolecular Research at the University of Toronto who led the work.The study also revealed the need for new therapy to take into account the genetic composition of tumours because of mu dunk low mujer tations in the cancer cells that can potentially make the disease worse in response to treatment, often referred to as cancer resistance mutations."It's very important to understand at the molecular level how cancer develops resist  KARACHI:The enrolment of students in district municipal corporation (DMC) schools in Lyari has surged for the new academic session.The enrolment of students has exceeded the 12,000 mark in the first two months of the academic year, which started in mid-April, whereas in 2016 the enrolment of students in 52 schools of Lyari zone from class one to nine was around 8,632.Reforms such as free education, teachers attendance, parent-teacher meetings, orientation of new students newbalance  and activities such as celebration of holidays like mother's day, father's day, art and colour day and st nb balance ipulated sports timings during school hour new balance 740 s has resulted in creating interest among the children of Lyari to attend school, according to students.Lyari girl bags top position in class six examsDeputy Lyari Zone Education Director Asma Ayaz told The Express Tribune that in more than eight schools the intake of students has been closed as there are no vacancies, while the vacancies in the remaining schools are quickly

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Egti Climate Change on Pace to Occur 10 Times Faster than any Change Recorded in Past 65 Million Years
  Although proteins have very different functions, or specialities, in living cells, they share the general characteristics -- the same universality -- in their motions, say University o yeezy boost f Oregon scientists.Their motion is much like mountain landslides or wildfires, reports the UO team in a paper published in the journal Physical Review Letters.The findings, which relied on theoretical methods developed in the lab of UO chemist Marina Guenza, may help pinpoint where protein binding could occur, and how protein motion is involved in the process."Dynamics is often unexplored in the study of protein binding, but it could be a determinant for the way proteins regulate their own biological activity," Guenza said. "Proteins in biological systems are constrained to a maximum size and move within a narrow, temperature-dependent window of time in which they are available to bi newbalance schuhe nd with other molecules, so it seems that all proteins should have some universal characteristics guidi yeezy schuhe ng their behaviour.   SEOUL, SOUTH KOREA:Handcuffed and bound with ropes, the heir of electronics giant Samsung appeared for questioning Saturday over his alleged involvement in the corruption scandal currently engulfing South Korean President Park Geun-Hye.Among other allegations, Lee is accused of paying nearly $40 million in bribes to a confidante of the impeached president to secure policy favours.Samsung chief questioned behind closed doors in arrest warrant hearingThe conglomer adidas samba og ate's de facto head stared straight ahead as he was greeted by a horde of journalists and camera flashes upon his arrival at the office of special prosecutors investigating the case.He kept silent as journalists fired questions at him, but the metal manacles could be glimpsed under the sleeves of his well- newbalance tailored, navy suit and white rope nb 574 s around his arms and back. A badge on his chest bore his prisoner number.During his first night at the Seoul Detention Centre, Lee was detained in a one-man cell instead of a six-person room -

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Qvyw Celebrating local authors: HEC gives national award to OUP book
  Takeda Pharmaceuticals Company Limited has announced that it will invest more than 100 Million E asic gels uros to nike dunk panda  build a new manufacturing plant for its dengue vaccine candidate in Singen, Germany. This represents a major step by Takeda toward meeting important unmet needs in dengue prevention. According to the World Health Organization (WHO), dengue is the fastest spreading mosquito-borne viral disease. Forty percent of the world鈥檚 population lives under the threat of the dengue virus, which causes an estimated 390 million infections and more than 20,000 deaths each year around the world in people of all ages.鈥淭his manufacturing plant investment reinforces Takeda鈥檚 strong support for our global vaccine strategy in general, and dengue in particular. The new plant will provide millions of p yeezys eople with access to a medicine that addresses a huge unmet medical need. It underlines our commitment to improve the lives of people worldwide,鈥?says Dr. Thomas Wozniewski, Global Manufacturing & Supply O  President Obama chaired his last Nuclear Security Summit on April 1, and his concerns today are no less great than when he chaired his first six years ago. Indeed, concerns regarding nuclear security 鈥?or insecurity 鈥?have risen over the last six years rather than diminished. He delivered a terrible warning that 鈥渕admen鈥?could kill or injure tens of thousands of people using a pie adidas campus grau ce of plutonium no larger than an apple. The possibility of a terrorist group obtaining and then using a crude nuclear device, a 鈥榙irty bomb鈥?is today one of the greatest threats to global zapatillas nb  security. The meeting of 50 world adidas campus beige  leaders, including a delegation from Pakistan, considered not only the possibility of nuclear materials falling into the wrong hands but chemical weapons as well. The Islamic State has used chemical weapons, including mustard gas, in Syria and Iraq and is believed still to have stocks in the inventory, and al Qaeda continues to seek nuclear material. It is not only terrorist groups that give

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Myih Former FIFA chief Joao Havelange passes away at 100
  Once mercury is emitted into the atmosphere from the smokestacks of power plants, the pollutant has a complicated trajectory; even after it settles onto land and sinks into oceans, mercury can be re-emitted back into the atmosphere repeatedly. This so-called 鈥済rasshopper effect yeezys 鈥?keeps the highly toxic substance circulating as 鈥渓egacy emissions鈥?that, combined with new smokestack emissions, can extend the environmental effects of mercury for decades.Now an international team led by MIT researchers has conducted a new analysis that provides more accurate estimates of sources of mercury emissions around the world. The analysis pairs measured air concentrations of mercury with a global simulation to calculate the fraction of mercury that is either re-emitted or that originates from power plants and other anthropogenic activities. The result of this work, researchers say, could improve estimates of mercury pollution, and help ref yeezy sneakers ine pollution-control dunk homme  strategies around the world.The new anal  KARACHI:The director of the Karachi health office  campus adidas has issued an alert to hospitals for heatwave, saying that the situation this year will be similar to the one in 2015, in which hundreds of people lost their lives due to escalating temperatures.The notice reads that since the unprecedented heatwave in Karachi in 2015 claimed the lives of many people, especially the elderly and c nb hildren, we need to be better prepared this time. "We are expecting the same situation this year,鈥?read the alert. 鈥淜eeping the previous experience in mind, we have to prepare ourselves before time [to combat this].鈥滷orewarned is forearmed:聽鈥榃e need to be better prepared for the heatwaves鈥橳he general notice was issued to the executive director of Jinnah Postgraduate Medical Centre and medical superintendents  adidas campus homme of Civil Hospital and general hospitals in Korangi, Ibrahim Hyderi, Saudabad and Liaquatabad, Qatar Hospital in Orangi Town, children鈥檚 hospital North Nazimabad and Abbasi Shaheed Hospital among others.The a

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Iksc IPS Extends Global Reach with Local Brazil Office
  For the first time, engineers have demonstrated an electronic device to closely monitor beating heart cells without affecting their behavior. A collaboration between the University of Tokyo, Tokyo Women's Medical University and RIKEN in Jap adidas yeezys an produced a functional sample of heart cells with a soft nanomesh sensor in direct contact with the tissue. This device could aid study of other cells, organs and medicines. It also paves the way for future embedded medical devices.Inside each of us beats a life-sustaining  nike dunk low heart. Unfortunately, the organ is not always perfect and sometimes goes wrong. One way or another research on the heart is fundamentally important to us all. So when Sunghoon Lee, a researcher in Professor Takao Someya's group at  Scarpe Yeezy the University of Tokyo, came up with the idea for an ultrasoft electronic sensor that could monitor functioning cells, his team jumped at the chance to use this sensor to study heart cells, or cardiomyocytes, as they beat."When researchers study cardio  RAWALPINDI:The Christian community of the twin cities bade farewell to Rufin Anthony, bishop for the Roman Catholic Diocese of Islamabad-Rawalpindi, on Wednesday in a solemn funeral at St Joseph鈥?adidas campus 00s s Cathedral in Lal Kurti.The bishop had died on October 17 after a prolonged illness.Bishop Anthony w adidas samba negras as laid to rest in Christian graveyard near Lal Kurti. His funeral was attended by thousands of people, including the bishops of Faisalabad, Hyderabad, Multan, and Apostolic Nuncio to Pakistan Archbishop Ghaleb Bader.Bishop Joseph Arshad from Faisalabad led the funeral prayers.Talking to The Express Tribune, Father Hilary of Sacred Heart Catholic Church in Westridge, said he had known the Bishop since 2012 and found him very humble and full of spirit for public service.Bishop Anthony was ordained as a priest in 1969, and was ordained as a bishop in 2009. He became bishop for I nb 550 slamabad-Rawalpindi in 2010.Published in The Express Tribune, October 20th, 2016.

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Fhfw DNA Nanostructures Capable of Self-healing
  Rosetta Genomics, Ltd. has announced that the results of a joint study with the NYU Langone Medical Center were published online on February 16th, 2010, and are set to be published in the March 1st issue of the American Association  yeezys 700 for Cancer Research??s journal, Cancer Research.The study, ??Hsa-Mir-29c* is Linked to the Prognosis of Mal yeezy boost ignant Pleural Mesothelioma,?? demonstrates the potential of a single microRNA to act as an independent prognostic factor for time to progression as well as survival after surgery.In the study, 142 MPM tumors were analyzed for microRNA expression levels using Rosetta Genomics?? proprietary microRNA-based array and qRT-PCR technologies. The results clearly demonstrate that hig yeezys her levels of miR-29c* in MPM predict a more favorable prognosis. Not only was the microRNA able to separate MPM patients by time to progression after surgery, but it also stratified these patients by their survival.When examining Time to Progression (TTP) of MPM, the expression level o  Hours after the Muttahida Qaumi Movement (MQM) cut off all ties with party chief??Altaf Hussain, he officially handed over??complete power to the??Rabita Committee."I am handing over complete power related to policy making, decision making as well as organisational authority to the Rabita Committee," the MQM supremo??said while praying??to God to??grant Rabita Committee the a ugg mini bility to serve the country??and its people, as best??as possible.MQM's decisions will be taken in Pakistan, Farooq tells Altaf"Leader Altaf Hussain endorses Rabita Committee's presser; tasks RC to deal with organisationa adidas campus donna l/political issues," ??MQM convenor??Nadeem Nusrat said??on Twitter.#MQM leader Altaf Hussain endorses Rabita Committee's presser; tasks RC to deal with organisational/political issues pic.twitter.com/I8EtPJz5lo— Dr. Nadeem Nusrat (@nadeem_nusrat) August 23, 2016As Hussain's??anti-Pakistan speech t newbalance 530 riggered countrywide uproar and widespread condemnation, his senior aides ??completely disowned?? his rema

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Esmx Ghost schools still haunt Sindh education sector
  Based on lab-on-a-chip micro-fluidics the PlugMaker has several key features:鈥ow sample volume: 5-10 nL/experiment; up to 800 experiments / 4 uL pro asics gelkayano tein 鈥o dead-volume, therefore no loss of protein sample 鈥nables systematic assessment of optimal protein yeezy boost  'crystallization slot' through optimization screens 鈥rystals directly amenable to X-ray diffraction experiments with standard equipment 鈥rystals can be readily extracted for traditional cryo-preservation 鈥ow cost per experiment Optimal protein crystallization growth conditions can be identified by systematic variation of one or two chemical components. MPCS鈩?fine gradient screening via automated on-chip formulation is a powerful optimization tool that allows thorough interroga af1 shoes tion of specific regions of crystallization phase space. Sparse matrix screening is achieved with the Plug Maker鈩?using the Hybrid Mode. In the Hybrid Mode, a pre-formed cartridge from a 96-well plate, containing a series of precipitants is generated and comb  ISLAMABAD:Imran Khan鈥檚 lawyers are repeating old pleas, and narrating old stories in the Panama Papers case in the Supreme Court, said Minister of State for Information, Broadcasting and National Heritage Marriyum Aurangzeb. She said this while talking to the media, adding that Imran should once aga campus adidas beige in change his lawyers who failed to produce any evidence in the court on Tuesday. The minster also advised Imran to reconsider Panama Papers case which was based on baseless allegations and lies, and asked him to withdraw the petition from the Supreme Court. Marriyum said that the PML-N has provided concrete proofs and documents in the court which reflect complete tr adidas samba blancas uth. She urged the PTI chairman to pay attention to Khyber-Pakhtunkhwa where people have been waiting for him to deliver.Published in The Express Tribune, December 7th,  stanley-cup 2016.

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Iyjo Two references against Sharifs returned
  A new study researchers at theSwiss Feder jordan low al Institute of Technology Zurich(ETH Zurich) in collaboration with experts from theInstitut de Ci猫ncies del Mar(ICM-CSIC), published in the prestigious journalNaturehas revealed the existence of a new family of marine bacteria whose genetic capacity, through the immense number of biosynthetic gene clusters in their genomes (BGCs), could lead to numerous biotechnological applications.The family belongs to the phylum Eremiobacterota, and until now was thought to exist only in terrestrial environments. However, according to the work published now, these bacteria are also found in the ocean. "In addition to being part of a very diverse bacte nb sneakers 574 rial group from a biosynthetic poi yeezy boost nt of view, these bacteria are ubiquitously and abundantly distributed throughout the ocean water column," explainsShinichi Sunagawa, professor at ETH Z眉rich and head of the team that led the study.Lucas Paoli, researcher at ETH Z眉rich and first author of the study, highlights t  Culture is not a rigid entity that is unforgiving of any factor that seems alien to it. In today鈥檚 world, almost every state is multicultural. It may not house many national adidas samba og ities or ethnicities, but even within its ostensibly unanimous population, stark differences exist, in the form of social class and background.To posit feminism and multiculturalism as oppositional is to assume that minority women are victims of their cultures. Pitting feminism against multiculturalism not only obscures the influences that shape cultural practices but assumes that the subjugation of women exists only in sub-cultures and not within the Western ideal. The question that new balance femme  whether or not and to what extent are feminism and multiculturalism compatible seems inherently flawed not because they are two polar opposites trying to reconcile with one anot campus adidas femme her; on the contrary, they can be amalgamated very neatly into an overlapping box, but the issue exists with the stance itself 鈥?the attempt at trying to work ou

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Otnp Torrential rains leave 42 dead in Balochistan, K-P: officials
  Increased frontal brain activity in healthy older adults reflects reduced efficiency rather than a way to maintain cognitive function, finds a study of two human samples published in JNeurosci. The findings contradict a leading theory in the neuroscience of aging.The Posterior-to-Anterior Shift in Aging (PASA) theory suggests the distribution of neural activity shifts from the back to the front of the brain over the lifesp dunk low an to compensate for typical age-related decline in executive functions such as memory. Alexa Morcom and Richard Henson tested predictions of this theory by analyzing functional magnetic resonance imaging data obtained from adults between 19 and 88 years chanclas yeezy  of age. Their approach allowed the researchers to determine that increased prefrontal cortex activity does not carry any additional information related to participants' performance on two di yeezy 700 fferent memory tasks. In contrast to the PASA theory, these results suggest that increased prefrontal cortex in aging is less spe  HYDERABAD:A Customs official was shot dead late Saturday night during a raid in the limits of Market police station.鈥淲e were uploading the contraband items seized during the raid when shots were fired [and ugg boots tasmania  the Customs officer was hit],鈥?additional collector Omar Shafique told The Express Tribune. The slain inspector Abdul Ghaffar Shaikh was among the 10-member team who raided the godown owned by Haji Ayub. He was shot in the head and was declared dead on arrival at a hospital. Shafique sai stanley d Ayub and his sons illegally import gutka from India, adding that the estimated worth of the seized contraband items is around Rs7.5 million. Three suspects were also held during the raid, along with seven others, including a 鈥榣ynchpin鈥? in follow-up raids by the Market police.Published in The Express Tribune, March 7th adidas campus bianche , 2016.